ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

Part Used : -

Activity : CYTOTOXICITY INHIBITION

Solvent/Active Compound : epigallocatechin-gallate (EGCG), (+)-catechin (C), (-)-epicatechin (EC), (-)-epigallocatechin (EGC), (-)-epicatechin-gallate (ECG)

Type of experiment : in vitro

Type of animal : -

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : -

Dose/Conc.(herb) : -

Duration : -

Type of interaction : Pharmacokinetics

Interaction with drug : Tacrolimus

Dose/Conc.(drug) : -

Result : Positive

Remark : The combined treatment with 5 micromolar EGCG and 5 micromolar of C, EC, EGC or ECG reduced FK506 (tacrolimus)-induced cytotoxicity in LLC-PK1. Similarty, the combined treatment with 5 micromolar EGC and 5 micromolar of C, EC, EGCG or ECG also reduced the cytotoxicity.

Note : Data incomplete

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