Synonym |
Thai / English name |
Part Used : รากActivity : CYP3A INHIBITIONSolvent/Active Compound : 18 beta-glycyrrhetic acid (18beta-GA)Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 10 micromolarsDuration : -Type of interaction : PharmacokineticsInteraction with drug : Midazolam*/Versed/DormicumDose/Conc.(drug) : -Result : PositiveRemark : Type of experiment: Human liver microsomes Result: 18 beta-GA, DAG, 20(S)-GF1 and Rh1 significantly inhibited CYP3A activity (44, 41, 23 and 15% inhibition, respectively)
Part Used : รากActivity : CYP3A INHIBITIONSolvent/Active Compound : 18 alpha-glycyrrhetic acid (18 alpha-GA)Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 10 micromolarsDuration : -Type of interaction : PharmacokineticsInteraction with drug : Midazolam*/Versed/DormicumDose/Conc.(drug) : -Result : NegativeRemark : Type of experiment: Human liver microsomes Result: 18alpha-GA and AG did not show statistical inhibition on the formation rate of 1'-hydroxymidazolam.