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| Thai / English name |
Part Used : เหง้าActivity : DRUG INTERACTIONSolvent/Active Compound : Ginger extract (selected Chinese ginger)Type of experiment : humanType of animal : -Type of study : Double-blind trialN(Total) : 56N(Treatment) : -Sex : Both sexAge : 66 yrs (mean) (24-87 yrs)Route : Oral administrationDose/Conc.(herb) : 170 mg ginger extract tidDuration : 3 wksType of interaction : Non-specifiedInteraction with drug : Ibuprofen*/Para-isobutylhydratropic acidDose/Conc.(drug) : 400 mg. tid (maximum 3 g. daily)Result : NegativeRemark : A ranking of efficacy of the three treatment periods: lbuprofen>ginger extract>placebo was found for visual analogue scale of pain. In the cross-over study, no significant difference between placebo and ginger extract could be demonstrated while explorative tests of differences in the first treatment period showed a better effect of both Ibuprofen and ginger extract than placebo.Note : Ginger extract was compared to placebo and lbuprofen in patients with osteoarthritis of the hip or knee in a controlled, double blind, double dummy, cross-over study with a wash-out period of one week followed by three treatment periods in a randomized sequence, each of three weeks duration.
Part Used : เหง้าActivity : DRUG INTERACTIONSolvent/Active Compound : Ginger extract (selected Chinese ginger)Type of experiment : humanType of animal : -Type of study : Cross overN(Total) : 56N(Treatment) : -Sex : Both sexAge : 66 yrs (mean) (24-87 yrs)Route : Oral administrationDose/Conc.(herb) : 170 mg ginger extract tidDuration : 3 wksType of interaction : Non-specifiedInteraction with drug : Ibuprofen*/Para-isobutylhydratropic acidDose/Conc.(drug) : 400 mg. tid (maximum 3 g. daily)Result : NegativeRemark : A ranking of efficacy of the three treatment periods: lbuprofen>ginger extract>placebo was found for visual analogue scale of pain. In the cross-over study, no significant difference between placebo and ginger extract could be demonstrated while explorative tests of differences in the first treatment period showed a better effect of both Ibuprofen and ginger extract than placebo.Note : Ginger extract was compared to placebo and lbuprofen in patients with osteoarthritis of the hip or knee in a controlled, double blind, double dummy, cross-over study with a wash-out period of one week followed by three treatment periods in a randomized sequence, each of three weeks duration.
