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Thai / English name |
Part Used : รำActivity : EFFECTS ON PHARMACOKINETICSolvent/Active Compound : -Type of experiment : humanType of animal : -Type of study : Cross overN(Total) : 7N(Treatment) : 7Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 35 gDuration : 168 h after the administration of phenprocoumonType of interaction : PharmacokineticsInteraction with drug : Phenprocoumon*/PhenprocoumarolDose/Conc.(drug) : -Result : PositiveRemark : Following the ingestion of wheat bran, a decreased absorption rate for phenprocoumon but no decrease in overall bioavailability was observed. In addition, a decrease in total body clearance of phenprocoumon and an increase in the free plasma fraction of phenprocoumon, resulting in decreased free drug clearance, was seen after wheat bran administration.Note : Data incomplete.
Part Used : รำActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : humanType of animal : -Type of study : Cross overN(Total) : 7N(Treatment) : 7Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 35 gDuration : 168 h after the administration of phenprocoumonType of interaction : PharmacokineticsInteraction with drug : Phenprocoumon*/PhenprocoumarolDose/Conc.(drug) : -Result : PositiveRemark : Following the ingestion of wheat bran, a decreased absorption rate for phenprocoumon but no decrease in overall bioavailability was observed. In addition, a decrease in total body clearance of phenprocoumon and an increase in the free plasma fraction of phenprocoumon, resulting in decreased free drug clearance, was seen after wheat bran administration.Note : Data incomplete.