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| Thai / English name |
Part Used : -Activity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 10 micromolarDuration : -Type of interaction : Non-specifiedInteraction with drug : 5-fluorouracil (5-FU)*/Fluorouracil/FUDose/Conc.(drug) : -Result : PositiveRemark : Combining curcumin with 5-fluorouracil (5-FU) significantly increased growth inhibition of AGS cells compared with either curcumin or 5-FU alone (P<0.05).Note : Data incomplete.
Part Used : เหง้าActivity : CYCLOOXYGENASE 2 INHIBITIONSolvent/Active Compound : curcuminType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : -Type of interaction : PharmacokineticsInteraction with drug : 5-fluorouracil (5-FU)*/Fluorouracil/FUDose/Conc.(drug) : -Result : PositiveRemark : The level of COX-2 protein expression was reduced almost 6-fold after combination treatment. The results demonstrate synergism between curcumim and 5-FU at higher doses against the human colon cancer cell line HT-29 which associated with the decreased expression of COX-2 protein.
Part Used : เหง้าActivity : DRUG INTERACTIONSolvent/Active Compound : curcuminType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : -Type of interaction : PharmacokineticsInteraction with drug : 5-fluorouracil (5-FU)*/Fluorouracil/FUDose/Conc.(drug) : -Result : PositiveRemark : The level of COX-2 protein expression was reduced almost 6-fold after combination treatment. The results demonstrate synergism between curcumim and 5-FU at higher doses against the human colon cancer cell line HT-29 which associated with the decreased expression of COX-2 protein.
