ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

Part Used : -

Activity : DRUG INTERACTION

Solvent/Active Compound : -

Type of experiment : in vivo

Type of animal : -

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : Non-specified

Dose/Conc.(herb) : 1 micromolar

Duration : -

Type of interaction : Pharmacodynamics

Interaction with drug : Cyclophosphamide*/CPM/CTX/CYT

Dose/Conc.(drug) : -

Result : Negative

Remark : Using an in vivo model of human breast cancer, dietary supplementation with curcumin was found to significantly inhibit cyclophosphamide-induced tumor regression. Such dietary supplementation was accompanied by a decrease in the activation of apoptosis by cyclophosphamide, as well as decreased the c-Jun NH2-terminal Kinase (JNK) activation.

Note : Data incomplete.

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