Part Used : -
Activity : DRUG INTERACTION
Solvent/Active Compound : Curcuminoids
Type of experiment : in vivo
Type of animal : mouse
N(Total) : -
N(Treatment) : -
Route : Oral administration
Dose/Conc.(herb) : 200 mg/kg/day
Duration : 2 mo.
Type of interaction : Pharmacodynamics
Interaction with drug : Deferiprone
Dose/Conc.(drug) : -
Remark : - Tretment with curcuminoids and deferiprone decreased levels of the Non-transferrin bound iron (NTBI) and malondialdehyde (MDA) effectively.
- Importantly, the curcuminoids and deferiprone reduced liver weight index and iron accumulation.