Part Used : น้ำจากผล
Activity : CYP2E1 INHIBITION
Solvent/Active Compound : -
Type of experiment : in vitro
Type of animal : -
N(Total) : -
N(Treatment) : -
Route : -
Dose/Conc.(herb) : 7.81-250 mg/ml
Duration : -
Type of interaction : Pharmacokinetics
Interaction with drug : -
Dose/Conc.(drug) : -
Remark : Type of experiment: mouse hepatic microsomes
Results: The bananas decreased the MROD activity, with no effect on the ENDM, EROD and ANH activities.
Note : Four enzymatic reactions: ethoxyresorufin O-deethylation (EROD) for CYP1A1, ethoxyresorufin O-demethylation (MROD) for CYP1A2, aniline hydroxylation (ANH) for CYP2E1, and erythromycin N-demethylation (ENDM) for CYP3A11.