ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

Part Used : หัว

Activity : CYP3A5 INHIBITION

Solvent/Active Compound : -

Type of experiment : in vitro

Type of animal : -

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : -

Dose/Conc.(herb) : -

Duration : -

Type of interaction : Pharmacokinetics

Interaction with drug : -

Dose/Conc.(drug) : -

Result : Positive

Remark : Garlic constituents have been shown to modulate the activity of various CYP isozymes in vitro. These constituents exhibit and inhibitory effect on CYP2C9* 1, CYP2C19, CYP3A4, CYP3A5, and CYP3A7 metabolism, whereas no effect on CYP2D6 was observed.

Note : Data incomplete, data from review article

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