ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

AMARYLLIDACEAE Allium sativum L.

Synonym

none ...

Thai / English name

กระเทียม*

[1-2] of 2 article(s) found

หน้า 1

[1] INTERACTIONS BETWEEN HERBAL AND CONVENTIONAL MEDICINES: THE ROLE OF CYTOCHROME P450 ENZYMES AND P-GLYCOPROTEIN.
WILLIAMSON EM
PHARMACOLOGYONLINE 2006 Vol.2(),200-5 $29296 [Full]

Part Used : ไม่ระบุ
Activity : CYP2B1/2 INDUCTION

Solvent/Active Compound :

Type of experiment : human
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : -

Duration : -
Type of interaction : Pharmacokinetics

Interaction with drug : -
Dose/Conc.(drug) : -

Result : Negative

Remark : Reduction of CYP2E1 activity in humans and some animal species; no increase in CYP2B1/2 in humans.

Note : Data incomplete, data from review article.

[2] INTERACTIONS BETWEEN HERBAL AND CONVENTIONAL MEDICINES: THE ROLE OF CYTOCHROME P450 ENZYMES AND P-GLYCOPROTEIN.
WILLIAMSON EM
PHARMACOLOGYONLINE 2006 Vol.(2),200-5 $56391 [Full]

Part Used : ไม่ระบุ
Activity : CYP2B1/2 INDUCTION

Solvent/Active Compound :

Type of experiment : human
Type of animal : -

Type of study : non specified

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : Non-specified
Dose/Conc.(herb) : -

Duration : -
Type of interaction : Pharmacokinetics

Interaction with drug : -
Dose/Conc.(drug) : -

Result : Negative

Remark : Reduction of CYP2E1 activity in humans and some animal species; no increase in CYP2B1/2 in humans. Mild inhibition of Pgp in vitro. Single reports of increased bleeding time with lisinopril, warfarin. Reduces bioavailability of the protease inhibitor saquinavir and to a lesser extent ritonavir. Appears safe with most drugs except saquinavir.

Note : Data from review, data incomplete.

หน้า 1

EN

Web Link ที่เกี่ยวข้อง

ที่อยู่