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CRUCIFERAE (BRASSICACEAE) Brassica spp.

Synonym

none ...

Thai / English name

Brassica spp.

[3-5] of 5 article(s) found

หน้า 1 2

[3] MODULATING POTENTIAL OF L-SULFORAPHANE IN THE EXPRESSION OF CYTOCHROME P450 TO IDENTIFY POTENTIAL TARGETS FOR BREAST CANCER CHEMOPREVENTION AND THERAPY USING BREAST CELL LINES.
BARBARA LICZNERSKA,HANNA SZAEFER,IWONA MATUSZAK,ET AL.
PHYTOTHER RES 2015 Vol.29(),93-9 $53971 [Full]

Part Used : ไม่ระบุ
Activity : DRUG INTERACTION

Solvent/Active Compound : L-sulforaphane (SFN)

Type of experiment : in vitro
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : 20 micromolars/L

Duration : 72 hours
Type of interaction : Pharmacokinetics

Interaction with drug : -
Dose/Conc.(drug) : -

Result : Positive

Remark : Type of experiment: Breast cancer cell lines MCF7.

Part Used : ไม่ระบุ
Activity : DRUG INTERACTION

Solvent/Active Compound : L-sulforaphane (SFN)

Type of experiment : in vitro
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : 5 micromolars/L

Duration : 72 hours
Type of interaction : Pharmacokinetics

Interaction with drug : -
Dose/Conc.(drug) : -

Result : Positive

Remark : Type of experiment: Breast cancer cell lines MDA-MB-231.

Part Used : ไม่ระบุ
Activity : DRUG INTERACTION

Solvent/Active Compound : L-sulforaphane (SFN)

Type of experiment : in vitro
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : 20 micromolars/L

Duration : 72 hours
Type of interaction : Pharmacokinetics

Interaction with drug : -
Dose/Conc.(drug) : -

Result : Positive

Remark : Type of experiment: Breast cancer cell lines MDA-MB-231.

Part Used : ไม่ระบุ
Activity : DRUG INTERACTION

Solvent/Active Compound : L-sulforaphane (SFN)

Type of experiment : in vitro
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : 5 micromolars/L

Duration : 72 hours
Type of interaction : Pharmacokinetics

Interaction with drug : -
Dose/Conc.(drug) : -

Result : Positive

Remark : Type of experiment: Non-tumorigenic MCF10A.

Part Used : ไม่ระบุ
Activity : DRUG INTERACTION

Solvent/Active Compound : L-sulforaphane (SFN)

Type of experiment : in vitro
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : 10 micromolars/L

Duration : 72 hours
Type of interaction : Pharmacokinetics

Interaction with drug : -
Dose/Conc.(drug) : -

Result : Positive

Remark : Type of experiment: Non-tumorigenic MCF10A.

[4] ENHANCING ACTIVITY OF ANTICANCER DRUGS IN MULTIDRUG RESISTANT TUMORS BY MODULATING P-GLYCOPROTEIN THROUGH DIETARY NUTRACEUTICALS.
MUHAMMAD KHAN,AMARA MARYAM,TAHIR MEHMOOD,ET AL.
ASIAN PAC J CANCER PREV 2015 Vol.16(16),6831-9 $59875 [Full]

Part Used : ใบ
Activity : DRUG INTERACTION

Solvent/Active Compound : Indol-3-Carbinol (l-3-C)

Type of experiment : in vitro
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : -

Duration : -
Type of interaction : Pharmacokinetics

Interaction with drug : Doxorubicin*/Adrimycin/ADR/Adria
Dose/Conc.(drug) : -

Result : Positive

Remark : Dietary intake of such vegetables contains that high amount of l-3-C to inhibit p-glycoprotein expression and activity in human body.

Note : Data from review

[5] EFFECTS OF DIETARY CHEMOPREVENTIVE PHYTOCHEMICALS ON P-GLYCOPROTEIN FUNCTION.
NABEKURA T,KAMIYAMA S,KITAGAWA S
BIOCHEM BIOPHYS RES COMMUN 2005 Vol.327(3),866-70 407084 [Abstract]

Part Used : -
Activity : DRUG INTERACTION

Solvent/Active Compound : sulforaphane, indole-3-carbinol

Type of experiment : in vitro
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : -

Duration : -
Type of interaction : Pharmacokinetics

Interaction with drug : Daunorubicin*/Daunomycin/Rubidomycin
Dose/Conc.(drug) : -

Result : Negative

Remark : Sulforaphane, indole-3-carbinol, and diallyl sulfide and diallyl trisulfide had no effect on P-glycoprotein.

หน้า 1 2

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