ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

Part Used : ราก

Activity : PROTHROMBIN TIME INCREASE

Solvent/Active Compound : -

Type of experiment : in vivo

Type of animal : rabbit

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : Oral administration

Dose/Conc.(herb) : -

Duration : 3 days

Type of interaction : P.Kinetics & P.Dynamics

Interaction with drug : Warfarin

Dose/Conc.(drug) : -

Result : Positive

Remark : The effects of root of Angelica sinensis (RAS) on the pharmacokinetics and pharmacodynamics of warfarin in rabbits showed RAS treatment did not affect prothrombin time (PT) by itself, but significantly lowered PT values three days after co-treatment with single dose warfarin. The results indicate that precautionasy advice should be given to patients who self-medicate with RAS while on chronic treatment with warfarin.

Note : Data from reviews article.

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