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| Thai / English name |
Part Used : ใบActivity : RECEPTOR BINDING STIMULANTSolvent/Active Compound : bilobalide (BB)Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : BB 50 microMDuration : Transfected cells were then treated with BB for 24 h.Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : NegativeRemark : Result: Transfection of CYP2B6-2.2 kb in the absence of exogenous Nuclear receptor (NRs) attest that endogenous Pregnane X receptor (PXR) and Constitutive androstane receptor (CAR) in HepG2 cells only exhibit negligible activation of the reporter compared with the potent response when exogenous PXR or CAR was included.Note : Abbreviations: AhR = Arylhydrocarbon receptor GA = Ginkgolide A, GB = Ginkgolide B, CAR = Constitutive androstane receptor, BB = Bilobalide, Que = Quercetin, Kae = Kaempferol, Tam = Tamarexetin
Part Used : ใบActivity : RECEPTOR BINDING STIMULANTSolvent/Active Compound : The standardized Ginkgo biloba leaf extract (EGb 761)Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : EGb 761 100 mcg/mlDuration : Transfected cells were then treated with EGb for 24 h.Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : NegativeRemark : Result: Transfection of CYP2B6-2.2 kb in the absence of exogenous Nuclear receptor (NRs) attest that endogenous Pregnane X receptor (PXR) and Constitutive androstane receptor (CAR) in HepG2 cells only exhibit negligible activation of the reporter compared with the potent response when exogenous PXR or CAR was included.Note : Abbreviations: AhR = Arylhydrocarbon receptor GA = Ginkgolide A, GB = Ginkgolide B, CAR = Constitutive androstane receptor, BB = Bilobalide, Que = Quercetin, Kae = Kaempferol, Tam = Tamarexetin
Part Used : ใบActivity : RECEPTOR BINDING STIMULANTSolvent/Active Compound : quercetin (Que)Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : Que 25 mcg/mlDuration : Transfected cells were then treated with Que for 24 h.Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : NegativeRemark : Result: Transfection of CYP2B6-2.2 kb in the absence of exogenous Nuclear receptor (NRs) attest that endogenous Pregnane X receptor (PXR) and Constitutive androstane receptor (CAR) in HepG2 cells only exhibit negligible activation of the reporter compared with the potent response when exogenous PXR or CAR was included.Note : Abbreviations: AhR = Arylhydrocarbon receptor GA = Ginkgolide A, GB = Ginkgolide B, CAR = Constitutive androstane receptor, BB = Bilobalide, Que = Quercetin, Kae = Kaempferol, Tam = Tamarexetin
Part Used : ใบActivity : RECEPTOR BINDING STIMULANTSolvent/Active Compound : kaempferol (Kae)Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : Kae 20 mcg/mlDuration : Transfected cells were then treated with Kae for 24 h.Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : NegativeRemark : Result: Transfection of CYP2B6-2.2 kb in the absence of exogenous Nuclear receptor (NRs) attest that endogenous Pregnane X receptor (PXR) and Constitutive androstane receptor (CAR) in HepG2 cells only exhibit negligible activation of the reporter compared with the potent response when exogenous PXR or CAR was included.Note : Abbreviations: AhR = Arylhydrocarbon receptor GA = Ginkgolide A, GB = Ginkgolide B, CAR = Constitutive androstane receptor, BB = Bilobalide, Que = Quercetin, Kae = Kaempferol, Tam = Tamarexetin
Part Used : ใบActivity : RECEPTOR BINDING STIMULANTSolvent/Active Compound : tamarixetin (Tam)Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : Tam 10 mcg/mlDuration : Transfected cells were then treated with Tam for 24 h.Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : NegativeRemark : Result: Transfection of CYP2B6-2.2 kb in the absence of exogenous Nuclear receptor (NRs) attest that endogenous Pregnane X receptor (PXR) and Constitutive androstane receptor (CAR) in HepG2 cells only exhibit negligible activation of the reporter compared with the potent response when exogenous PXR or CAR was included.Note : Abbreviations: AhR = Arylhydrocarbon receptor GA = Ginkgolide A, GB = Ginkgolide B, CAR = Constitutive androstane receptor, BB = Bilobalide, Que = Quercetin, Kae = Kaempferol, Tam = Tamarexetin
