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Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 100 mg/kg BWDuration : three dyas before and seven days after the treatment with cisplatinType of interaction : PharmacodynamicsInteraction with drug : Cisplatin*/CDDPDose/Conc.(drug) : 7 mg/kg at 4th day of the treatmentResult : PositiveRemark : Type of experiment: The exptl. groups were as follows: Control group, Cisplatin-treated group (Cisplatin), and a group treated with Cisplatin plus Ginkgo biloba extract (GBE). Results: Ginkgo biloba extract may prevent kidney damage caused by cisplatin.Note : Data incomplete
Part Used : ใบActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : in vivoType of animal : guinea pigType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : -Duration : -Type of interaction : P.Kinetics & P.DynamicsInteraction with drug : Cisplatin*/CDDPDose/Conc.(drug) : -Result : PositiveRemark : Combined use of extract of EGb and DFO could effectively reduce the ototoxicity of cisplatin, its effect is better than using EGb singly, and similar to that of using DFO alone.Note : Type of experiment: Guinea pigs were randomly divided into the cisplatin group, the Ginkgo leaf (EGb) group, the deferoxamine (DFO) group, the combined treated group (EGb+DFO) and the control group. Data incomplete
