ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

Part Used : ใบ

Activity : CYP2C9 INHIBITION

Solvent/Active Compound : -

Type of experiment : human

Type of animal : -

Type of study : Double-blind trial

N(Total) : 11

N(Treatment) : 11

Sex : -

Age : -

Route : Oral administration

Dose/Conc.(herb) : *

Duration : -

Type of interaction : Pharmacokinetics

Interaction with drug : Flurbiprofen

Dose/Conc.(drug) : -

Result : Equivocal

Remark : Dose: * Single 100 mg dose of flurbiprofen + standardized G. biloba leaf preposition (Ginkgold, 3 doses of 120 mg) - Each 60 mg Ginkgold tablet contained 6.6 microgram of amentoflavone and 61.2 microgram of quercetin. - Mean kinetic variables for flurbiprofen with either placebo or G. biloba were elimination half-life, 3.9 vs. 3.5 h; total AUC, 57 vs. 55 microgram/mL per hour; and oral clearance 32.9 vs. 31.6 mL/min. None of these differences was significant.

Note : - Data incomplete

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