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Part Used : ทั้งต้นActivity : ANTIHEPATOTOXIC ACTIVITYSolvent/Active Compound : standardized extract of Phyllanthus amarusType of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : IntraperitonealDose/Conc.(herb) : silymarin (50 mg/kg b.w.) + Phyllanthus amarus aqueous extract (50 mg/kg b.w.)Duration : 6 daysType of interaction : PharmacodynamicsInteraction with drug : Silymarin*/Silybin BDose/Conc.(drug) : -Result : PositiveRemark :Note : Result: The combination of silymarin and Phyllanthus amarus showed synergistic effect for hepatoprotection and silymarin with ethanolic extract of P. amarus showed better activity due to the higher concentration of phyllanthin in ethanolic extract in comparison to aqueous extract of P. amarus as estimated by HPLC.
Part Used : ทั้งต้นActivity : ANTIHEPATOTOXIC ACTIVITYSolvent/Active Compound : standardized extract of Phyllanthus amarusType of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : IntraperitonealDose/Conc.(herb) : silymarin (50 mg/kg b.w.) + Phyllanthus amarus ethanolic extract (50 mg/kg b.w.)Duration : 6 daysType of interaction : PharmacodynamicsInteraction with drug : Silymarin*/Silybin BDose/Conc.(drug) : -Result : PositiveRemark :Note : Result: The combination of silymarin and Phyllanthus amarus showed synergistic effect for hepatoprotection and silymarin with ethanolic extract of P. amarus showed better activity due to the higher concentration of phyllanthin in ethanolic extract in comparison to aqueous extract of P. amarus as estimated by HPLC.
