ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

Part Used : เมล็ด

Activity : DRUG INTERACTION

Solvent/Active Compound : procyanidin

Type of experiment : in vitro

Type of animal : -

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : -

Dose/Conc.(herb) : -

Duration : -

Type of interaction : Pharmacokinetics

Interaction with drug : Paclitaxel*/Taxol/PTX

Dose/Conc.(drug) : -

Result : Positive

Remark : Grape seed procyanidin reversed MDR by inhibiting the function and expression of p-glycoprotein via inhibition of NF-kappaB and gammaB-1 translocation intonucleus through dephosphorylation of AKT and ERK1/2 respectively.

Note : Data from review

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