Synonym |
Thai / English name |
Part Used : หัวActivity : DRUG INTERACTIONSolvent/Active Compound : quercetinType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : -Type of interaction : PharmacokineticsInteraction with drug : Doxorubicin*/Adrimycin/ADR/AdriaDose/Conc.(drug) : -Result : PositiveRemark : Quercetin could enhance the anticancer activity of doxorubicin against multidrug resistant MCF-7 breast carcinoma by inhibiting the expression and activity of p-glycoprotein at a very low concentration of 0.7 micromolar.Note : Data from review
Part Used : ใบActivity : DRUG INTERACTIONSolvent/Active Compound : quercetinType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : -Type of interaction : PharmacokineticsInteraction with drug : Doxorubicin*/Adrimycin/ADR/AdriaDose/Conc.(drug) : -Result : PositiveRemark : Quercetin could enhance the anticancer activity of doxorubicin against multidrug resistant MCF-7 breast carcinoma by inhibiting the expression and activity of p-glycoprotein at a very low concentration of 0.7 micromolar.Note : Data from review
Part Used : หัวActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : humanType of animal : -Type of study : Double-blind trialN(Total) : 46N(Treatment) : 23Sex : FemaleAge : 30-65 yrs.Route : Oral administrationDose/Conc.(herb) : BMI < 24.9 cosumed fresh onion 100-120 g/day, BMI > 25 cosumed fresh onion 140-160 g/dayDuration : 8 weeksType of interaction : PharmacokineticsInteraction with drug : Doxorubicin*/Adrimycin/ADR/AdriaDose/Conc.(drug) : -Result : PositiveRemark : The effectiveness of onion to control CEA and CA125 tumor markers. But they were not significant between groups at the end of study among BC patients during doxorubicin (DOX) based chemotherapy. Manipulation of diet through high intake of onion is promising to possibly improve a synergistic effect on DOX-based chemotherapy.Note : Patients were breast cancer (BC) participants treated with doxorubicin
Part Used : หัวActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : humanType of animal : -Type of study : Double-blind trialN(Total) : 46N(Treatment) : 23Sex : FemaleAge : 30-65 yrs.Route : Oral administrationDose/Conc.(herb) : fresh onion 30-40 g/day (control)Duration : 8 weeksType of interaction : PharmacokineticsInteraction with drug : Doxorubicin*/Adrimycin/ADR/AdriaDose/Conc.(drug) : -Result : PositiveRemark : The effectiveness of onion to control CEA and CA125 tumor markers. But they were not significant between groups at the end of study among BC patients during doxorubicin (DOX) based chemotherapy. Manipulation of diet through high intake of onion is promising to possibly improve a synergistic effect on DOX-based chemotherapy.Note : Patients were breast cancer (BC) participants treated with doxorubicin