| Synonym |
| Thai / English name |
Part Used : ดอกActivity : DRUG INTERACTIONSolvent/Active Compound : saponinType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : 24-72 hoursType of interaction : PharmacodynamicsInteraction with drug : Cyclophosphamide*/CPM/CTX/CYTDose/Conc.(drug) : -Result : PositiveRemark : - Study in Human erythroleukemic cell line K562. - Ginseng saponin could completely inhibit the telomerase activity of K562 cells at proper concentration and exposure time and the inhibiting effects were enhanced when used in combination with cyclophosphamide.Note : Data incomplete
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : humanType of animal : -Type of study : Cross-sectionN(Total) : 233N(Treatment) : -Sex : FemaleAge : -Route : Oral administrationDose/Conc.(herb) : -Duration : -Type of interaction : PharmacokineticsInteraction with drug : Tamoxifen*/TAMDose/Conc.(drug) : -Result : PositiveRemark : The study identified use of 35 different typed of complimentary alternative medicine products and seven of these could potentially increase the risk of breast cancer or interact with tamoxifen or aromatase inhibitiors: soy, garlic, Ginkgo biloba, Echinacea, ginseng, velerian and phytoestrogens (excluding soy).Note : Data incomplete Subject were consecutive breast cancer patients
Part Used : เหง้าActivity : DRUG INTERACTIONSolvent/Active Compound : 25-hydroxyprotopanaxadiol (25-OH-PPD)Type of experiment : in vivoType of animal : mouseType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Non-specifiedDose/Conc.(herb) : -Duration : -Type of interaction : PharmacodynamicsInteraction with drug : Docetaxel*/TaxotereDose/Conc.(drug) : -Result : PositiveRemark : Results: In nude mice bearing PC3 xenograft tumors, 25-OH-PPD inhibited tumor growth in a dose dependent manner and could be safely combined with chemotherapeutic agents (taxotere and gemcitabine) and radiation therapy to improve the anti-tumor effects.Note : Data incomplete.
Part Used : เหง้าActivity : DRUG INTERACTIONSolvent/Active Compound : 25-hydroxyprotopanaxadiol (25-OH-PPD)Type of experiment : in vivoType of animal : mouseType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Non-specifiedDose/Conc.(herb) : -Duration : -Type of interaction : PharmacodynamicsInteraction with drug : GemcitabineDose/Conc.(drug) : -Result : PositiveRemark : Results: In nude mice bearing PC3 xenograft tumors, 25-OH-PPD inhibited tumor growth in a dose dependent manner and could be safely combined with chemotherapeutic agents (taxotere and gemcitabine) and radiation therapy to improve the anti-tumor effects.Note : Data incomplete.
Part Used : เหง้าActivity : DRUG INTERACTIONSolvent/Active Compound : 25-hydroxyprotopanaxadiol (25-OH-PPD)Type of experiment : in vivoType of animal : mouseType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Non-specifiedDose/Conc.(herb) : -Duration : -Type of interaction : PharmacodynamicsInteraction with drug : Docetaxel*/TaxotereDose/Conc.(drug) : -Result : NegativeRemark :Note : Data incomplete.
Part Used : เหง้าActivity : DRUG INTERACTIONSolvent/Active Compound : 25-hydroxyprotopanaxadiol (25-OH-PPD)Type of experiment : in vivoType of animal : mouseType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Non-specifiedDose/Conc.(herb) : -Duration : -Type of interaction : PharmacodynamicsInteraction with drug : GemcitabineDose/Conc.(drug) : -Result : NegativeRemark :Note : Data incomplete.
Part Used : -Activity : DRUG INTERACTIONSolvent/Active Compound : (20S)-20-O-beta-D-Glucopyranosyl-protopanaxadiolType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : -Type of interaction : PharmacokineticsInteraction with drug : Cyclophosphamide*/CPM/CTX/CYTDose/Conc.(drug) : -Result : PositiveRemark : Comparing the antitumor activity of (20S)-20-O-beta-D-Glucopyranosyl-protopanaxadiol (1) plus cyclophosphamide (CTX) with that of CTX alone, the combination effect was significantly superior and synergistic. This may due to immunoregulation activity of 1 by improving the WBC, IL-2 and INF-gamma degraded by CTX.Note : Data from abstract
Part Used : -Activity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : humanType of animal : -Type of study : non specifiedN(Total) : 75N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : -Duration : -Type of interaction : PharmacokineticsInteraction with drug : Metoprolol*/Metoprolol succinateDose/Conc.(drug) : -Result : PositiveRemark : Metoprolol succinate sustained-release tablet combined with Shengmai decoction has good curative effect on chronic congestive heart failure.Note : Subject = patients with heart failure were randomly divided into groups A, B, and C. Group A was treated with Shengmai decoction*, group B with metoprolol succinate sustained-release tablet, and group C with metoprolol succinate sustained-release tablet combined with Shengmai decoction. *Sheng-Mai decoction: Panax gingeng, Ophiopogon japonicas, Shisandra chinensis Data from abstract
Part Used : -Activity : DRUG INTERACTIONSolvent/Active Compound : ginsenoside Rg3Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : The combination of Rg3 and chemotherapeutic agents can reduce the toxicity and increase therapeutic effects.Note : Data from abstract
