Synonym |
Thai / English name |
Part Used : -Activity : CYP1A2 INDUCTIONSolvent/Active Compound : Ginsenoside S-Rg3Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 0.1 microgram/mLDuration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : NegativeRemark : Induction potential of 0.1 microgram/mL ginsenoside S-Rg3 on activities of CYP1A2, CYP2B6 and CYP3A4/5 in three different lots of cryopreserved human hepatocytes. Fold increase enzyme activity in each CYP were 0.989 +/- 0.112, 1.03 +/- 0.164, and 0.872 +/- 0.0500, respectively.
Part Used : -Activity : CYP1A2 INDUCTIONSolvent/Active Compound : Ginsenoside S-Rg3Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 1 microgram/mLDuration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : NegativeRemark : Induction potential of 1 microgram/mL ginsenoside S-Rg3 on activities of CYP1A2, CYP2B6 and CYP3A4/5 in three different lots of cryopreserved human hepatocytes. Fold increase enzyme activity in each CYP were 0.989 +/- 0.0884, 1.04 +/- 0.144, and 0.849 +/- 0.0706, respectively.
Part Used : -Activity : CYP1A2 INDUCTIONSolvent/Active Compound : Ginsenoside S-Rg3Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 10 microgram/mLDuration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : NegativeRemark : Induction potential of 10 microgram/mL ginsenoside S-Rg3 on activities of CYP1A2, CYP2B6 and CYP3A4/5 in three different lots of cryopreserved human hepatocytes. Fold increase enzyme activity in each CYP were 1.09 +/- 0.0739, 1.03 +/- 0.0516, and 0.846 +/- 0.0438, respectively.
Part Used : -Activity : CYP1A2 INDUCTIONSolvent/Active Compound : Ginsenoside S-Rh2Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 0.1 microgram/mLDuration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : NegativeRemark : Induction potential of 0.1 microgram/mL ginsenoside S-Rh2 on activities of CYP1A2, CYP2B6 and CYP3A4/5 in three different lots of cryopreserved human hepatocytes. Fold increase enzyme activity in each CYP were 1.02 +/- 0.014, 1.07 +/- 0.0285, and 0.961 +/- 0.0320, respectively.
Part Used : -Activity : CYP1A2 INDUCTIONSolvent/Active Compound : Ginsenoside S-Rh2Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 1 microgram/mLDuration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : NegativeRemark : Induction potential of 1 microgram/mL ginsenoside S-Rh2 on activities of CYP1A2, CYP2B6 and CYP3A4/5 in three different lots of cryopreserved human hepatocytes. Fold increase enzyme activity in each CYP were 0.959 +/- 0.0106, 1.23 +/- 0.211, and 0.885 +/- 0.0419, respectively.
Part Used : -Activity : CYP1A2 INDUCTIONSolvent/Active Compound : Ginsenoside S-Rh2Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 10 microgram/mLDuration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : NegativeRemark : Induction potential of 10 microgram/mL ginsenoside S-Rh2 on activities of CYP1A2, CYP2B6 and CYP3A4/5 in three different lots of cryopreserved human hepatocytes. Fold increase enzyme activity in each CYP were 1.03 +/- 0.0160, 1.08 +/- 0.400, and 0.835 +/- 0.0347, respectively.
Part Used : -Activity : CYP1A2 INDUCTIONSolvent/Active Compound : Ginsenoside R-Rh2Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 0.1 microgram/mLDuration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : NegativeRemark : Induction potential of 01 microgram/mL ginsenoside S-Rh2 on activities of CYP1A2, CYP2B6 and CYP3A4/5 in three different lots of cryopreserved human hepatocytes. Fold increase enzyme activity in each CYP were 0.946 +/- 0.0442, 0.987 +/- 0.112, and 0.910 +/- 0.0513, respectively.
Part Used : -Activity : CYP1A2 INDUCTIONSolvent/Active Compound : Ginsenoside S-Rh2Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 1 microgram/mLDuration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : NegativeRemark : Induction potential of 1 microgram/mL ginsenoside S-Rh2 on activities of CYP1A2, CYP2B6 and CYP3A4/5 in three different lots of cryopreserved human hepatocytes. Fold increase enzyme activity in each CYP were 0.961 +/- 0.0621, 1.023 +/- 0.0650, and 0.881 +/- 0.114, respectively.
Part Used : -Activity : CYP1A2 INDUCTIONSolvent/Active Compound : Ginsenoside S-Rh2Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 10 microgram/mLDuration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : NegativeRemark : Induction potential of 10 microgram/mL ginsenoside S-Rh2 on activities of CYP1A2, CYP2B6 and CYP3A4/5 in three different lots of cryopreserved human hepatocytes. Fold increase enzyme activity in each CYP were 1.04 +/- 0.0633, 1.13 +/- 0.191, and 0.860 +/- 0.0586, respectively.