| Synonym |
| Thai / English name |
Part Used : เหง้าActivity : DRUG INTERACTIONSolvent/Active Compound : red ginseng powderType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : -Type of interaction : PharmacokineticsInteraction with drug : MethoxyfluraneDose/Conc.(drug) : -Result : NegativeRemark : - Twenty rats were divided into 4 groups (n=5) as follows: group 1 - control, group 2-4 fed with red ginseng powder 15, 75 and 200 mg/kg/day, respectively. Red ginseng powder was dissolved in deionized water based on 20 ml/rat/day. After 2 weeks of drinking ad libitum they were killed and collected liver microsomes for measurement of protein content and anesthetic defluorination activity. - The rates of enflurane and methoxyflurane defluorination by rat liver microsomes determined by incubation of 10 microliters of each anesthetic with 5 mg of microsomal protein.Note : There were no statistically significant differences in hepatic microsomal cytochrome p-450 content or defluorination of enflurane and methoxyflurane between control and experimental groups using either red ginseng extract or powder.
Part Used : เหง้าActivity : DRUG INTERACTIONSolvent/Active Compound : red ginseng powderType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) :Duration :Type of interaction : PharmacokineticsInteraction with drug : MethoxyfluraneDose/Conc.(drug) : -Result : NegativeRemark : - Twenty four rats were divided into 4 groups (n=6) as follows: group 1 - control, group 2-4 red ginseng extract 62.5, 125 and 250 mg/kg/day, respectively. Each dose was dissolved in 0.9% saline (0.5 ml) and administered with 22G gavage needle three times a day for three days. End of study rats were killed and collected liver microsomes for measurement of protein content and anesthetic defluorination activity. - The rates of enflurane and methoxyflurane defluorination by rat liver microsomes determined by incubation of 10 microliters of each anesthetic with 5 mg of microsomal protein.Note : There were no statistically significant differences in hepatic microsomal cytochrome p-450 content or defluorination of enflurane and methoxyflurane between control and experimental groups using either red ginseng extract or powder.
