Synonym |
Thai / English name |
Part Used : เหง้าActivity : DRUG INTERACTIONSolvent/Active Compound : red ginseng acidic polysaccharideType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : -Type of interaction : PharmacodynamicsInteraction with drug : Cyclophosphamide*/CPM/CTX/CYTDose/Conc.(drug) : -Result : PositiveRemark : The red ginseng acidic polysaccharide consists of 41.5-61.5% of glucuronic acid, 3.9-5.9% of galacturonic acid, 15.1-35.1% of glucose, and 0.5-2.5% of arabinose and has a molecular weight of 12,000-450,000 Da.Note : Data incomplete.
Part Used : ดอกActivity : DRUG INTERACTIONSolvent/Active Compound : saponinType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : 24-72 hoursType of interaction : PharmacodynamicsInteraction with drug : Cyclophosphamide*/CPM/CTX/CYTDose/Conc.(drug) : -Result : PositiveRemark : - Study in Human erythroleukemic cell line K562. - Ginseng saponin could completely inhibit the telomerase activity of K562 cells at proper concentration and exposure time and the inhibiting effects were enhanced when used in combination with cyclophosphamide.Note : Data incomplete
Part Used : -Activity : DRUG INTERACTIONSolvent/Active Compound : (20S)-20-O-beta-D-Glucopyranosyl-protopanaxadiolType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : -Type of interaction : PharmacokineticsInteraction with drug : Cyclophosphamide*/CPM/CTX/CYTDose/Conc.(drug) : -Result : PositiveRemark : Comparing the antitumor activity of (20S)-20-O-beta-D-Glucopyranosyl-protopanaxadiol (1) plus cyclophosphamide (CTX) with that of CTX alone, the combination effect was significantly superior and synergistic. This may due to immunoregulation activity of 1 by improving the WBC, IL-2 and INF-gamma degraded by CTX.Note : Data from abstract