Part Used : ราก
Activity : CYP3A INHIBITION
Solvent/Active Compound : 20(S)-ginsenoside F1 (20(S)-GF1), ginsenoside Rh1(Rh1)
Type of experiment : in vitro
Type of animal : -
N(Total) : -
N(Treatment) : -
Route : -
Dose/Conc.(herb) : 10 micromolars
Duration : -
Type of interaction : Pharmacokinetics
Interaction with drug : Midazolam*/Versed/Dormicum
Dose/Conc.(drug) : -
Remark : Type of experiment: Human liver microsomes
Result: 18 beta-GA, DAG, 20(S)-GF1 and Rh1 significantly inhibited CYP3A activity (44, 41, 23 and 15% inhibition, respectively)