ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

Part Used : น้ำจากผล

Activity : CYTOCHROME P-450 INHIBITION

Solvent/Active Compound : Furanocoumarins, Fruit juices of Guanximiyou (Citrus grandis Osbeck vs. Guanxi)

Type of experiment : in vitro

Type of animal : -

Type of study : -

N(Total) :

N(Treatment) :

Sex : -

Age : -

Route : Oral administration

Dose/Conc.(herb) :

Duration :

Type of interaction : Pharmacokinetics

Interaction with drug : Felodipine

Dose/Conc.(drug) :

Result : Positive

Remark : Results: Citrus paradisi had more furanocoumarins and at higher levels than C. grandis Osbeck vs. Guanxi while C. changshanhuyou Y.B. Chang hand none, and their potencies for in vitro CYP3A inhibition were in the order as C. paradisi > C. grandis Osbeck vs. Guanxi > C. changshanhuyou Y.B. Chang.

Note : Data incomplete.

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