ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

Part Used : น้ำจากผล

Activity : DRUG INTERACTION

Solvent/Active Compound : -

Type of experiment : human

Type of animal : -

Type of study : Cross over

N(Total) : 10*

N(Treatment) : 10

Sex : -

Age : -

Route : Oral administration

Dose/Conc.(herb) : *

Duration : *

Type of interaction : Pharmacokinetics

Interaction with drug : Atenolol

Dose/Conc.(drug) : 50 mg

Result : Positive

Remark : The av. heart rate was slightly higher during the orange juice+atenold phase than during the water+atenolol phase.

Note : Data incomplete *In randomized cross-over study with two phases and a washout of 2 wk, ten healthy volunteers took either 200 mL orange juice or water thrice daily for 3 days and twice on the fourthy day. On the morning of day 3, each subject ingested 50 mg atenolol with an addnl. amt. of either 200 mL orange juice or water.

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