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| Thai / English name |
Part Used : น้ำจากผลActivity : DRUG INTERACTIONSolvent/Active Compound : tangeretinType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : Uptake experiments were performed in 250 ml of incubation buffer containing 20 mM [3H]vinblastine in the presence of tangeretin 20 microMDuration : 60 min.Type of interaction : PharmacokineticsInteraction with drug : Vinblastine*/VLBDose/Conc.(drug) : 20 mM [3H]vinblastineResult : PositiveRemark : Result: In LLC-PK1 cells, the uptake of [3H]vinblastine at steady state was not influenced by 10 mM cyclosporin A, HMF, tangeretin, or nobiletin.
Part Used : น้ำจากผลActivity : EFFECTS ON PHARMACOKINETICSolvent/Active Compound : tangeretinType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : Uptake experiments were performed in 250 ml of incubation buffer containing 20 mM [3H]vinblastine in the presence of tangeretin 20 microMDuration : 60 min.Type of interaction : PharmacokineticsInteraction with drug : Vinblastine*/VLBDose/Conc.(drug) : 20 mM [3H]vinblastineResult : PositiveRemark : Result: In LLC-PK1 cells, the uptake of [3H]vinblastine at steady state was not influenced by 10 mM cyclosporin A, HMF, tangeretin, or nobiletin.
Part Used : น้ำจากผลActivity : DRUG INTERACTIONSolvent/Active Compound : nobiletinType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : Uptake experiments were performed in 250 ml of incubation buffer containing 20 mM [3H]vinblastine in the presence of nobitetin 20 microMDuration : 60 min.Type of interaction : PharmacokineticsInteraction with drug : Vinblastine*/VLBDose/Conc.(drug) : 20 mM [3H]vinblastineResult : PositiveRemark : Result: In LLC-PK1 cells, the uptake of [3H]vinblastine at steady state was not influenced by 10 mM cyclosporin A, HMF, tangeretin, or nobiletin.
Part Used : น้ำจากผลActivity : EFFECTS ON PHARMACOKINETICSolvent/Active Compound : nobiletinType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : Uptake experiments were performed in 250 ml of incubation buffer containing 20 mM [3H]vinblastine in the presence of nobitetin 20 microMDuration : 60 min.Type of interaction : PharmacokineticsInteraction with drug : Vinblastine*/VLBDose/Conc.(drug) : 20 mM [3H]vinblastineResult : PositiveRemark : Result: In LLC-PK1 cells, the uptake of [3H]vinblastine at steady state was not influenced by 10 mM cyclosporin A, HMF, tangeretin, or nobiletin.
Part Used : น้ำจากผลActivity : DRUG INTERACTIONSolvent/Active Compound : 3.3',4',5,6,7,8-heptamethoxyflavone (HMF)Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : Uptake experiments were performed in 250 ml of incubation buffer containing 20 mM [3H]vinblastine in the presence of HMF 20 microMDuration : 60 min.Type of interaction : PharmacokineticsInteraction with drug : Vinblastine*/VLBDose/Conc.(drug) : 20 mM [3H]vinblastineResult : PositiveRemark : Result: In LLC-GA5-COL300 cells, the uptake of [3H]vinblastine at steady state was significantly increased by 20 microM HMF (99.8 +/- 4.61 microliter/mg of protein) compared with the control (10.6 +/- 0.612 microliter/mg of protein).
Part Used : น้ำจากผลActivity : EFFECTS ON PHARMACOKINETICSolvent/Active Compound : 3.3',4',5,6,7,8-heptamethoxyflavone (HMF)Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : Uptake experiments were performed in 250 ml of incubation buffer containing 20 mM [3H]vinblastine in the presence of HMF 20 microMDuration : 60 min.Type of interaction : PharmacokineticsInteraction with drug : Vinblastine*/VLBDose/Conc.(drug) : 20 mM [3H]vinblastineResult : PositiveRemark : Result: In LLC-GA5-COL300 cells, the uptake of [3H]vinblastine at steady state was significantly increased by 20 microM HMF (99.8 +/- 4.61 microliter/mg of protein) compared with the control (10.6 +/- 0.612 microliter/mg of protein).
Part Used : น้ำจากผลActivity : DRUG INTERACTIONSolvent/Active Compound : tangeretinType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : Uptake experiments were performed in 250 ml of incubation buffer containing 20 mM [3H]vinblastine in the presence of tangeretin 20 microMDuration : 60 min.Type of interaction : PharmacokineticsInteraction with drug : Vinblastine*/VLBDose/Conc.(drug) : 20 mM [3H]vinblastineResult : PositiveRemark : Result: In LLC-GA5-COL300 cells, the uptake of [3H]vinblastine at steady state was significantly increased by 20 microM tangeretin (64.5 +/- 1.66 microliter/mg of protein) compared with the control (10.6 +/- 0.612 microliter/mg of protein).
Part Used : น้ำจากผลActivity : EFFECTS ON PHARMACOKINETICSolvent/Active Compound : tangeretinType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : Uptake experiments were performed in 250 ml of incubation buffer containing 20 mM [3H]vinblastine in the presence of tangeretin 20 microMDuration : 60 min.Type of interaction : PharmacokineticsInteraction with drug : Vinblastine*/VLBDose/Conc.(drug) : 20 mM [3H]vinblastineResult : PositiveRemark : Result: In LLC-GA5-COL300 cells, the uptake of [3H]vinblastine at steady state was significantly increased by 20 microM tangeretin (64.5 +/- 1.66 microliter/mg of protein) compared with the control (10.6 +/- 0.612 microliter/mg of protein).
Part Used : น้ำจากผลActivity : DRUG INTERACTIONSolvent/Active Compound : nobiletinType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : Uptake experiments were performed in 250 ml of incubation buffer containing 20 mM [3H]vinblastine in the presence of nobiletin 20 microMDuration : 60 min.Type of interaction : PharmacokineticsInteraction with drug : Vinblastine*/VLBDose/Conc.(drug) : 20 mM [3H]vinblastineResult : PositiveRemark : Result: In LLC-GA5-COL300 cells, the uptake of [3H]vinblastine at steady state was significantly increased by 20 microM nobiletin (18.6 +/- 2.05 microliter/mg of protein) compared with the control (10.6 +/- 0.612 microliter/mg of protein).
Part Used : น้ำจากผลActivity : EFFECTS ON PHARMACOKINETICSolvent/Active Compound : nobiletinType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : Uptake experiments were performed in 250 ml of incubation buffer containing 20 mM [3H]vinblastine in the presence of nobiletin 20 microMDuration : 60 min.Type of interaction : PharmacokineticsInteraction with drug : Vinblastine*/VLBDose/Conc.(drug) : 20 mM [3H]vinblastineResult : PositiveRemark : Result: In LLC-GA5-COL300 cells, the uptake of [3H]vinblastine at steady state was significantly increased by 20 microM nobiletin (18.6 +/- 2.05 microliter/mg of protein) compared with the control (10.6 +/- 0.612 microliter/mg of protein).
