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ASPHODELACEAE Aloe vera (L.) Burm.f.

Synonym

ASPHODELACEAE Aloe barbadensis Mill.
ASPHODELACEAE Aloe indica Royle

Thai / English name

ว่านหางจระเข้*

[1-1] of 1 article(s) found

หน้า 1

[1] USE OF ALOE VERA FOR INCREASING THE BIOAVAILABILITY OF POORLY ABSORBABLE MEDICINAL DRUGS.
HAMMAN JH,VILJOEN AM
PCT INT APPL WO 2009103093 2009 Vol.(),51pp $27204 [Full]

Part Used : วุ้นจากใบ
Activity : ABSORPTION ENHANCEMENT EFFECT

Solvent/Active Compound : Aloe vera gel

Type of experiment : in vitro
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : Aloe vera gel 0.10, 0.50, 1.00, 2.5 and 5.00%w/v

Duration : -
Type of interaction : Pharmacokinetics

Interaction with drug : Insulin
Dose/Conc.(drug) : -

Result : Positive

Remark : Result: Aloe vera gel was able to significantly (p<0.05) enhance the transport of insulin across Caco-2 cell monolayers in concentrations higher than 0.5%w/v

Part Used : ใบ
Activity : ABSORPTION ENHANCEMENT EFFECT

Solvent/Active Compound : Aloe vera whole leaf extract

Type of experiment : in vitro
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : Aloe vera whole leaf extract 0.10, 0.50, 1.00, 2.5 and 5.00%w/v

Duration : -
Type of interaction : Pharmacokinetics

Interaction with drug : Insulin
Dose/Conc.(drug) : -

Result : Positive

Remark : Result: The transport enhancement effect obtained with Aloe vera whole leaf extract on insulin was expected as it was able to decrease the transepithelial electrical resistance. (TEER) of the Caco-2 cell monolayers, which indicates opening of the tight junctions and thereby allow for increased paracellular transport across the epithelial cell layer.

หน้า 1

EN

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