Part Used : น้ำจากผล
Activity : DRUG INTERACTION
Solvent/Active Compound : Aloe vera juice
Type of experiment : in vitro
Type of animal : -
N(Total) : -
N(Treatment) : -
Route : -
Dose/Conc.(herb) : 0.00001 -1.0 mg/ml
Duration : -
Type of interaction : Pharmacodynamics
Interaction with drug : Digoxin
Dose/Conc.(drug) : -
Remark : None of these digoxin transport parameters were affected statistically significantly by any of the aloe vera juice concentrations applied, while verapamil (P-gp inhibitor) reduced both net digoxin flux and net digoxin Papp Net by 89% and 81%, respectively.
Papp = apparent permeability coefficient, Papp Net = net Papp values