ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

Part Used : น้ำจากผล

Activity : P-GLYCOPROTEIN INHIBITION

Solvent/Active Compound : Aloe vera juice

Type of experiment : in vitro

Type of animal : -

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : -

Dose/Conc.(herb) : 0.00001 -1.0 mg/ml

Duration : -

Type of interaction : Pharmacodynamics

Interaction with drug : Digoxin

Dose/Conc.(drug) : -

Result : Negative

Remark : None of these digoxin transport parameters were affected statistically significantly by any of the aloe vera juice concentrations applied, while verapamil (P-gp inhibitor) reduced both net digoxin flux and net digoxin Papp Net by 89% and 81%, respectively. Papp = apparent permeability coefficient, Papp Net = net Papp values

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