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LEGUMINOSAE (FABACEAE) - CAESALPINIOIDEAE Senna alexandrina Mill.

Synonym

LEGUMINOSAE (FABACEAE) - CAESALPINIOIDEAE Cassia acutifolia Delile
LEGUMINOSAE (FABACEAE) - CAESALPINIOIDEAE Cassia angustifolia Vahl
LEGUMINOSAE (FABACEAE) - CAESALPINIOIDEAE Cassia obovata Collad.
LEGUMINOSAE (FABACEAE) - CAESALPINIOIDEAE Cassia senna L.

Thai / English name

มะขามแขก*

[1-1] of 1 article(s) found

หน้า 1

[1] POTENTIAL OF DECURSIN TO INHIBIT THE HUMAN CYTOCHROME P450 2J2 ISOFORM.
BORAM LEE,ZHEXUE WU,SANG HYUN SUNG,ET AL.
FOOD CHEM TOXICOL 2014 Vol.70(),94-9 $51739 [Full]

Part Used : ไม่ระบุ
Activity : CYTOCHROME P-450 INHIBITION

Solvent/Active Compound : Sennoside A

Type of experiment : in vitro
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : 5 microgram/ml

Duration : -
Type of interaction : Pharmacokinetics

Interaction with drug : Astemizole
Dose/Conc.(drug) : 1 micromolar

Result : Negative

Remark : Sennoside A could not inhibit CYP2J2 catalyzed astemizole.

Part Used : ไม่ระบุ
Activity : CYTOCHROME P-450 INHIBITION

Solvent/Active Compound : Sennoside B

Type of experiment : in vitro
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : 5 microgram/ml

Duration : -
Type of interaction : Pharmacokinetics

Interaction with drug : Astemizole
Dose/Conc.(drug) : 1 micromolar

Result : Positive

Remark : Sennoside B inhibited CYP2J2 catalyzed astemizole with 28% inhibition.

หน้า 1

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