ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

Part Used : ใบ

Activity : DRUG INTERACTION

Solvent/Active Compound : -

Type of experiment : in vivo

Type of animal : rat

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : Oral administration

Dose/Conc.(herb) : 500 mg/kg

Duration : The anticonvulsant activity was assessed by the classical Maximal Electro Shock (MES) test at 1, 3, 6 and 24 h after drug administration.

Type of interaction : Pharmacodynamics

Interaction with drug : Phenytoin*/Diphenylhydantoin/DPH

Dose/Conc.(drug) : -

Result : Positive

Remark : Results: When Bacopa monnieri (BM) combined with antiepileptic drug significant seizure protection (p<0.05) was observed - with phenytoin a 6 h, with phenobarbitone at 3 h, and with carbama zepine, at 1,3 and 6 h.

Note : Data incomplete.

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