ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

Part Used : ใบ

Activity : DRUG INTERACTION

Solvent/Active Compound : extract of guava leaves (GvEx)

Type of experiment : in vivo

Type of animal : mouse

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : -

Dose/Conc.(herb) : GvEx 250 mg/kg

Duration : -

Type of interaction : Pharmacodynamics

Interaction with drug : Acarbose

Dose/Conc.(drug) : -

Result : Positive

Remark : The GvEx had no effect on the blood glucose-lowering effect of the drugs. However, when GvEx was administered to mice loaded with a high concentration cooked starch (without sucrose) together with acarbose or voglibose at a dose that failed to prevent the increase of the postprandial blood glucose level, there was a significant reduction in the rise of the blood glucose level. These results suggest that GvEx is useful for preventing the increase in the blood glucose level in combination with both acarbose and voglibose without having to increase the dose of these drugs.

Note : Data incomplete.

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