NELUMBONACEAE Nelumbo nucifera  Gaertn.

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 Thai / English name

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[1-1] of 1 article(s) found

 หน้า  1  

[1] THE IN VITRO INHIBITION OF HUMAN CYP1A2, CYP2D6 AND CYP3A4 BY TETRAHYDROPALMATINE, NEFERINE AND BERBERINE.
YONG ZHAO,BENT HVARD HELLUM,AIHUA LIANG,ET AL.
PHYTOTHER RES 2012 Vol.26(),277-83  $39525 [Full]

Part Used : เมล็ด
Activity : DRUG INTERACTION
Solvent/Active Compound : Neferine
Type of experiment : in vitro
Type of animal : -
Type of study : -
N(Total) : -
N(Treatment) : -
Sex : -
Age : -
Route : -
Dose/Conc.(herb) : 5 microliters
Duration : 10 minutes
Type of interaction : Pharmacokinetics
Interaction with drug : Testosterone
Dose/Conc.(drug) : -
Result : Positive
Remark : The IC50 values of neferine on CYP3A4 was 25.1+/-3.5 micromolar (15.7+/-2.1 micrograms/mL).


 หน้า  1