ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

Part Used : -

Activity : UDP-GLUCURONYL TRANSFERASE INHIBITION

Solvent/Active Compound : Andrographolide derivatives

Type of experiment : in vitro

Type of animal : -

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : -

Dose/Conc.(herb) : 100 micromolar

Duration : -

Type of interaction : Pharmacokinetics

Interaction with drug : Zidovudine*/AZT/ZDV/Azidothymidine

Dose/Conc.(drug) : -

Result : Positive

Remark :

Note : Andrographolide derivatives showed inhibition capabilities towards UDP-glucuronyl transferase (UGT) 2B7 and human liver microsome-catalyzed AZT glucuronidation.

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