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| Thai / English name |
Part Used : น้ำจากผลActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 2 mLDuration : -Type of interaction : PharmacokineticsInteraction with drug : Carbamazepine*/CBZDose/Conc.(drug) : 50 mg/kgResult : PositiveRemark : Pomegranate juice alters the carbamazepine pharmacokinetics in rats.Note : Data incomplete
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : -Type of interaction : PharmacodynamicsInteraction with drug : GenisteinDose/Conc.(drug) : -Result : PositiveRemark : Type of experiment: human breast cancer cells (MCF-7) Results: Both pomegranate extracts and genistein inhibit the growth of MCF-7 breast cancer cells through induction of apoptosis, with combination treatment being more efficacious than single treatments.Note : Data incomplets
Part Used : ผลActivity : DRUG INTERACTIONSolvent/Active Compound : Pomegranate methanolic extract (PGME)Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : -Type of interaction : PharmacodynamicsInteraction with drug : Chloramphenicol*/Chlornitromycin/Levomycetin/ChloromycetinDose/Conc.(drug) : -Result : PositiveRemark : Using this combination, cell viability was reduced by 99.9% and 72.5% in methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-sensitive Staphylococcus aureus (MSSA) populations, respectively. PGME increased the post-antibiotic effect (PAE) of ampicillin from 3 to 7 hours. In addition, PGME demonstrated the potential to either inhibit the efflux pump NorA or to enhance the influx of the drug.Note : Data in complete.
Part Used : ผลActivity : DRUG INTERACTIONSolvent/Active Compound : Pomegranate methanolic extract (PGME)Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : -Type of interaction : PharmacodynamicsInteraction with drug : GentamicinDose/Conc.(drug) : -Result : PositiveRemark : Using this combination, cell viability was reduced by 99.9% and 72.5% in methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-sensitive Staphylococcus aureus (MSSA) populations, respectively. PGME increased the post-antibiotic effect (PAE) of ampicillin from 3 to 7 hours. In addition, PGME demonstrated the potential to either inhibit the efflux pump NorA or to enhance the influx of the drug.Note : Data in complete.
Part Used : ผลActivity : DRUG INTERACTIONSolvent/Active Compound : Pomegranate methanolic extract (PGME)Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : -Type of interaction : PharmacodynamicsInteraction with drug : AmpicillinDose/Conc.(drug) : -Result : PositiveRemark : Using this combination, cell viability was reduced by 99.9% and 72.5% in methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-sensitive Staphylococcus aureus (MSSA) populations, respectively. PGME increased the post-antibiotic effect (PAE) of ampicillin from 3 to 7 hours. In addition, PGME demonstrated the potential to either inhibit the efflux pump NorA or to enhance the influx of the drug.Note : Data in complete.
Part Used : ผลActivity : DRUG INTERACTIONSolvent/Active Compound : Pomegranate methanolic extract (PGME)Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : -Type of interaction : PharmacodynamicsInteraction with drug : TetracyclineDose/Conc.(drug) : -Result : PositiveRemark : Using this combination, cell viability was reduced by 99.9% and 72.5% in methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-sensitive Staphylococcus aureus (MSSA) populations, respectively. PGME increased the post-antibiotic effect (PAE) of ampicillin from 3 to 7 hours. In addition, PGME demonstrated the potential to either inhibit the efflux pump NorA or to enhance the influx of the drug.Note : Data in complete.
Part Used : ผลActivity : DRUG INTERACTIONSolvent/Active Compound : Pomegranate methanolic extract (PGME)Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : -Type of interaction : PharmacodynamicsInteraction with drug : Oxacillin*/Oxazocillin/Methylphenylisoxazolyl (MPI) penicillin/Oxacilline/OxacillinumDose/Conc.(drug) : -Result : PositiveRemark : Using this combination, cell viability was reduced by 99.9% and 72.5% in methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-sensitive Staphylococcus aureus (MSSA) populations, respectively. PGME increased the post-antibiotic effect (PAE) of ampicillin from 3 to 7 hours. In addition, PGME demonstrated the potential to either inhibit the efflux pump NorA or to enhance the influx of the drug.Note : Data in complete.
Part Used : น้ำจากผลActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 25 microlit (5.0%v/v)Duration : -Type of interaction : PharmacokineticsInteraction with drug : Carbamazepine*/CBZDose/Conc.(drug) :Result : PositiveRemark : Type of experiment: Human liver microsome Addition of 25 microl (5% v/v) of pomegranate juice resulted in almost complete inhibition of the carbamazepine 10,11-epoxidase activity of human CYP3A (1.8%).Note : Data incomplete
