Part Used : ผล
Activity : P-GLYCOPROTEIN INHIBITION
Solvent/Active Compound : piperine
Type of experiment : in vitro
Type of animal : -
N(Total) : -
N(Treatment) : -
Route : -
Dose/Conc.(herb) : -
Duration : -
Type of interaction : Pharmacokinetics
Interaction with drug : Doxorubicin*/Adrimycin/ADR/Adria
Dose/Conc.(drug) : 50 micromolar
Remark : piperine inhibits the efflux activity of p-gp and alters the clinical pharmacokinetic profile of doxorubicin and several drug which are p-glycoprotein substrate.