| Synonym |
| Thai / English name |
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : n-butanol fraction of black teaType of experiment : in vitroType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 10 microgram/mLDuration : -Type of interaction : PharmacodynamicsInteraction with drug : Imipenem*/Imipemide/Imipenemum/N-formimidoylthienamycin/TienamycinDose/Conc.(drug) : 5 micromolarResult : PositiveRemark : Type of experiment: rat thymocyte. Black tea ext. and its n-butanol fraction also inhibited etoposide-induced apoptosis.Note : These results indicate that the ingestion of tea reduces the risk of the side effect of etoposide, which have been clin. administered in chemotherapy as an anticancer drug. Data incomplete
Part Used : ใบActivity : DRUG INTERACTIONSolvent/Active Compound : Oolong (Chinese tea)Type of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : -Duration : 4 weeksType of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : The activity of CYP1A1 in livers from rats receiving Oolong (Chinese) tea (185+/-63 pmol/mg/min) was significantly higher (p <0.05) than in the control group (94+/-34 pmol/mg/min).Note : - Female Wistar rats were divided into five group (n=4 each); each had free access to tea solutions while the control group was supplied with water. Data complete
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : catechinsType of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 0.25% catechinDuration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Cytochrome P450 levels in the catechin-free (MW-0C) group was increased by 85% compared with normal, but was 11% and 14% lower in the 0.25% catechin (MW-0.25C) and 0.5% catechin (MW-0.5C) groups than in the MW-0C group. NADPH-cytochrome P450 reductase activity in the MW-0C group was increased by 29%, compared with the normal group, but was significantly less in the MW-0.25C and MW-0.5C groups.Note : Data incomplete
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : catechinsType of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 0.5% catechinDuration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Cytochrome P450 levels in the catechin-free (MW-0C) group was increased by 85% compared with normal, but was 11% and 14% lower in the 0.25% catechin (MW-0.25C) and 0.5% catechin (MW-0.5C) groups than in the MW-0C group. NADPH-cytochrome P450 reductase activity in the MW-0C group was increased by 29%, compared with the normal group, but was significantly less in the MW-0.25C and MW-0.5C groups.Note : Data incomplete
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : green tea extractType of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 175 mg kg-1Duration : 4 daysType of interaction : PharmacokineticsInteraction with drug : ClozapineDose/Conc.(drug) : 20 mg kg-1Result : EquivocalRemark : There was no significant difference in the elimination half-life of clozapine between the green tea ext. and saline groups. However, the time to reach peak concn. (Tmax) was significantly increased by green tea ext. The mean total area under the plasma concn.-time curve (AUC0-infinity) and maximal peak plasma concn. (Cmax) of clozapine in the green tea ext. group were significantly lower than those of controls.Note : Data incomplete
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : in vivoType of animal : mouseType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 2.5% decaffeinated black tea ext. (DBTE)Duration : 15 daysType of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : NegativeRemark : Treatment with 2.5% decaffeinated black tea ext. (DBTE) or 1% polymeric black tea polyphenol (PBP) mix did not significantly alter the basal activity and level of CYP1A1 and CYP1A2.Note : Data incomplete
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : polyphenolType of experiment : in vivoType of animal : mouseType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 1% polymeric black tea polyphenol (PBP)Duration : 15 daysType of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : NegativeRemark : Treatment with 2.5% decaffeinated black tea ext. (DBTE) or 1% polymeric black tea polyphenol (PBP) mix did not significantly alter the basal activity and level of CYP1A1 and CYP1A2.Note : Data incomplete
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound :Type of experiment : in vivoType of animal : mouseType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 2.5% decaffeinated black tea ext. (DBTE)Duration : 15 daysType of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) :Result : PositiveRemark : Pretreatment with 2.5% decaffeinated black tea ext. (DBTE) or 1% polymeric black tea polyphenol (PBP) mix resulted in a significant decrease in both the activity and the level of B(a)P-induced CYP1A1 and CYP1A2 in liver and lungs.Note : Data incomplete
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : in vivoType of animal : mouseType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : 1% polymeric black tea polyphenol (PBP)Duration : 15 daysType of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) :Result : NegativeRemark : Pretreatment with 2.5% decaffeinated black tea ext. (DBTE) or 1% polymeric black tea polyphenol (PBP) mix resulted in a significant decrease in both the activity and the level of B(a)P-induced CYP1A1 and CYP1A2 in liver and lungs.Note : Data incomplete
Part Used : -Activity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : -Duration : -Type of interaction : PharmacokineticsInteraction with drug : Povidone-iodine*/Polyvinylpyrrolidone iodine/Betadine/Providine/Alphadine/IsodineDose/Conc.(drug) : -Result : PositiveRemark :Note : Green tea beverages reduce the antibacterial activity of povidone-iodine in proportion to their antioxidant activity. Data incomplete
