ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

Part Used : -

Activity : DRUG INTERACTION

Solvent/Active Compound : green tea polyphenols

Type of experiment : in vivo

Type of animal : mouse

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : Oral administration

Dose/Conc.(herb) : 0.1% in drinking water

Duration : -

Type of interaction : P.Kinetics & P.Dynamics

Interaction with drug : Celecoxib

Dose/Conc.(drug) : 5 mg/kg, i.p., daily, 5 days per weeks

Result : Positive

Remark : Type of animal: nude mice Results: Combination treatment with green tea polyphenols and celecoxib resulted in enhanced (a) tumor growth inhibition, (b) lowering of prostate-specific antigen levels, (c) lowering of insulin-like growth factor-l levels, and (d) circulating levels of serum insulin-like growth factor binding protein-3 compared with results of single-agent treatment.

Note : Data incomplete

---