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Part Used : ไม่ระบุ

Activity : CYP1A2 INHIBITION

Solvent/Active Compound : green tea exract

Type of experiment : in vivo

Type of animal : rat

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : Oral administration

Dose/Conc.(herb) : green tea extract 175 mg kg-1

Duration : 4 days

Type of interaction : Pharmacokinetics

Interaction with drug : Clozapine

Dose/Conc.(drug) : 20 mg kg-1

Result : Positive

Remark : Green tea extract induced a apprx.2-fold increase in hepatic CYP1A2 levels, while the activity increased slightly (by 10% of control).

Note : Data incomplete

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