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ZINGIBERACEAE Zingiber officinale Roscoe

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Thai / English name

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[24-25] of 25 article(s) found

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[24] GINGER-ASSOCIATED OVERANTICOAGULATION BY PHENPROCOUMON.
KRUTH P,BROSI E,FUX R,ET AL.
ANN PHARMACOTHER 2004 Vol.38(2),257-60 400350 [Abstract]

Part Used : ไม่ระบุ
Activity : DRUG INTERACTION

Solvent/Active Compound : -

Type of experiment : human
Type of animal : -

Type of study : Case report

N(Total) : 1
N(Treatment) : 1

Sex : Female
Age : 76 years

Route : Oral administration
Dose/Conc.(herb) : -

Duration : -
Type of interaction : Pharmacodynamics

Interaction with drug : Phenprocoumon*/Phenprocoumarol
Dose/Conc.(drug) : -

Result : Positive

Remark : A 76-year-old woman on long-term phenprocoumon therapy with an INR within the therapeutic range began using ginger products. Several weeks later, she developed an elevated INR up to 10 and epistaxis. The INR returned to the normal range after ginger was stopped and vitamin K1 was given.

Note : Data incomplete

[25] EFFECTS OF DIETARY CHEMOPREVENTIVE PHYTOCHEMICALS ON P-GLYCOPROTEIN FUNCTION.
NABEKURA T,KAMIYAMA S,KITAGAWA S
BIOCHEM BIOPHYS RES COMMUN 2005 Vol.327(3),866-70 407084 [Abstract]

Part Used : -
Activity : DRUG INTERACTION

Solvent/Active Compound : [6]-gingerol

Type of experiment : in vitro
Type of animal : -

Type of study : -

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : -
Dose/Conc.(herb) : -

Duration : -
Type of interaction : Pharmacokinetics

Interaction with drug : Daunorubicin*/Daunomycin/Rubidomycin
Dose/Conc.(drug) : -

Result : Positive

Remark : Sulforaphane, indole-3-carbinol, and diallyl sulfide and diallyl trisulfide had no effect on P-glycoprotein.

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