| Synonym |
| Thai / English name |
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : 6-ShogaolType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 10-50 micromolarsDuration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Type of experiment: HepG2 cellsNote : The mRNA expression levels of AHR-targeting drug metabolizing enzymes (CYP1A1, UGT1A1, ABCG2) and the protein level of CYP1A1 in HepG2 cells were induced by 6-shogaol.
Part Used : เหง้าActivity : DRUG INTERACTIONSolvent/Active Compound : EthanolType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 100 micrograms/mLDuration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Results: Extract of the formulations and its ingredients had higher solubility in DMSO than ethanol. It illustrated the highest percentage of inhibition: 37.54+/-3.12% (Trikatu marketed formulation), 35.12+/-2.31% (Trikatu laboratory formulation), 33.23+/-2.56% (6-gingerol), 31.36+/-3.42% (piperine), 17.35+/+1.50% (Zingiber officinale), 20.21+/-1.86% (Piper longum), and 16.67+/-2.83% (Piper nigrum). Lowest inhibition (24.81+/-2.57% and 26.38+/-2.57%) of piperine and 6-gingerol was observed with ethanol.Note : Type of experiment: rat liver microsomes. The amount of 6-gingerol present in extract of Zingiber officinal, Trikatumarketed formulation and Trikatu laboratory formulation was estimated to be about 6.21+/-1.03%, 5.3+/-1.21% and 4.95+/-2.34% (w/w), respectively. Piperine was found to be 7.31+/-2.36% (Piper longum), 8.41+/-2.54% (Piper nigrum), 7.89+/-2.12% (Trikatu marketed formulation) and 6.70+/-2.13% (w/w) (Trikatu laboratory formulation).
Part Used : เหง้าActivity : DRUG INTERACTIONSolvent/Active Compound : 6-gingerol ethanolType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 6-gingerol ethanol 10 micrograms/mLDuration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Results: Extract of the formulations and its ingredients had higher solubility in DMSO than ethanol. It illustrated the highest percentage of inhibition: 37.54+/-3.12% (Trikatu marketed formulation), 35.12+/-2.31% (Trikatu laboratory formulation), 33.23+/-2.56% (6-gingerol), 31.36+/-3.42% (piperine), 17.35+/+1.50% (Zingiber officinale), 20.21+/-1.86% (Piper longum), and 16.67+/-2.83% (Piper nigrum). Lowest inhibition (24.81+/-2.57% and 26.38+/-2.57%) of piperine and 6-gingerol was observed with ethanol.Note : Type of experiment: rat liver microsomes. The amount of 6-gingerol present in extract of Zingiber officinal, Trikatumarketed formulation and Trikatu laboratory formulation was estimated to be about 6.21+/-1.03%, 5.3+/-1.21% and 4.95+/-2.34% (w/w), respectively. Piperine was found to be 7.31+/-2.36% (Piper longum), 8.41+/-2.54% (Piper nigrum), 7.89+/-2.12% (Trikatu marketed formulation) and 6.70+/-2.13% (w/w) (Trikatu laboratory formulation).
Part Used : เหง้าActivity : DRUG INTERACTIONSolvent/Active Compound : DMSO (Dimethyl Sulfoxide)Type of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 100 micrograms/mLDuration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Results: Extract of the formulations and its ingredients had higher solubility in DMSO than ethanol. It illustrated the highest percentage of inhibition: 37.54+/-3.12% (Trikatu marketed formulation), 35.12+/-2.31% (Trikatu laboratory formulation), 33.23+/-2.56% (6-gingerol), 31.36+/-3.42% (piperine), 17.35+/+1.50% (Zingiber officinale), 20.21+/-1.86% (Piper longum), and 16.67+/-2.83% (Piper nigrum). Lowest inhibition (24.81+/-2.57% and 26.38+/-2.57%) of piperine and 6-gingerol was observed with ethanol.Note : Type of experiment: rat liver microsomes. The amount of 6-gingerol present in extract of Zingiber officinal, Trikatumarketed formulation and Trikatu laboratory formulation was estimated to be about 6.21+/-1.03%, 5.3+/-1.21% and 4.95+/-2.34% (w/w), respectively. Piperine was found to be 7.31+/-2.36% (Piper longum), 8.41+/-2.54% (Piper nigrum), 7.89+/-2.12% (Trikatu marketed formulation) and 6.70+/-2.13% (w/w) (Trikatu laboratory formulation).
Part Used : เหง้าActivity : DRUG INTERACTIONSolvent/Active Compound : 6-gingerol DMSOType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 6-gingerol DMSO 10 micrograms/mLDuration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Results: Extract of the formulations and its ingredients had higher solubility in DMSO than ethanol. It illustrated the highest percentage of inhibition: 37.54+/-3.12% (Trikatu marketed formulation), 35.12+/-2.31% (Trikatu laboratory formulation), 33.23+/-2.56% (6-gingerol), 31.36+/-3.42% (piperine), 17.35+/+1.50% (Zingiber officinale), 20.21+/-1.86% (Piper longum), and 16.67+/-2.83% (Piper nigrum). Lowest inhibition (24.81+/-2.57% and 26.38+/-2.57%) of piperine and 6-gingerol was observed with ethanol.Note : Type of experiment: rat liver microsomes. The amount of 6-gingerol present in extract of Zingiber officinal, Trikatumarketed formulation and Trikatu laboratory formulation was estimated to be about 6.21+/-1.03%, 5.3+/-1.21% and 4.95+/-2.34% (w/w), respectively. Piperine was found to be 7.31+/-2.36% (Piper longum), 8.41+/-2.54% (Piper nigrum), 7.89+/-2.12% (Trikatu marketed formulation) and 6.70+/-2.13% (w/w) (Trikatu laboratory formulation).
Part Used : เหง้าActivity : DRUG INTERACTIONSolvent/Active Compound : Trikatu laboratory formulation / EthanolType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 100 micrograms/mLDuration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Results: Extract of the formulations and its ingredients had higher solubility in DMSO than ethanol. It illustrated the highest percentage of inhibition: 37.54+/-3.12% (Trikatu marketed formulation), 35.12+/-2.31% (Trikatu laboratory formulation), 33.23+/-2.56% (6-gingerol), 31.36+/-3.42% (piperine), 17.35+/+1.50% (Zingiber officinale), 20.21+/-1.86% (Piper longum), and 16.67+/-2.83% (Piper nigrum). Lowest inhibition (24.81+/-2.57% and 26.38+/-2.57%) of piperine and 6-gingerol was observed with ethanol.Note : Type of experiment: rat liver microsomes. The amount of 6-gingerol present in extract of Zingiber officinal, Trikatumarketed formulation and Trikatu laboratory formulation was estimated to be about 6.21+/-1.03%, 5.3+/-1.21% and 4.95+/-2.34% (w/w), respectively. Piperine was found to be 7.31+/-2.36% (Piper longum), 8.41+/-2.54% (Piper nigrum), 7.89+/-2.12% (Trikatu marketed formulation) and 6.70+/-2.13% (w/w) (Trikatu laboratory formulation).
Part Used : ผลActivity : DRUG INTERACTIONSolvent/Active Compound : Trikatu laboratory formulation / EthanolType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 100 micrograms/mLDuration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Results: Extract of the formulations and its ingredients had higher solubility in DMSO than ethanol. It illustrated the highest percentage of inhibition: 37.54+/-3.12% (Trikatu marketed formulation), 35.12+/-2.31% (Trikatu laboratory formulation), 33.23+/-2.56% (6-gingerol), 31.36+/-3.42% (piperine), 17.35+/+1.50% (Zingiber officinale), 20.21+/-1.86% (Piper longum), and 16.67+/-2.83% (Piper nigrum). Lowest inhibition (24.81+/-2.57% and 26.38+/-2.57%) of piperine and 6-gingerol was observed with ethanol.Note : Type of experiment: rat liver microsomes. The amount of 6-gingerol present in extract of Zingiber officinal, Trikatumarketed formulation and Trikatu laboratory formulation was estimated to be about 6.21+/-1.03%, 5.3+/-1.21% and 4.95+/-2.34% (w/w), respectively. Piperine was found to be 7.31+/-2.36% (Piper longum), 8.41+/-2.54% (Piper nigrum), 7.89+/-2.12% (Trikatu marketed formulation) and 6.70+/-2.13% (w/w) (Trikatu laboratory formulation).
Part Used : เหง้าActivity : DRUG INTERACTIONSolvent/Active Compound : Trikatu laboratory formulation / DMSOType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 100 micrograms/mLDuration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Results: Extract of the formulations and its ingredients had higher solubility in DMSO than ethanol. It illustrated the highest percentage of inhibition: 37.54+/-3.12% (Trikatu marketed formulation), 35.12+/-2.31% (Trikatu laboratory formulation), 33.23+/-2.56% (6-gingerol), 31.36+/-3.42% (piperine), 17.35+/+1.50% (Zingiber officinale), 20.21+/-1.86% (Piper longum), and 16.67+/-2.83% (Piper nigrum). Lowest inhibition (24.81+/-2.57% and 26.38+/-2.57%) of piperine and 6-gingerol was observed with ethanol.Note : Type of experiment: rat liver microsomes. The amount of 6-gingerol present in extract of Zingiber officinal, Trikatumarketed formulation and Trikatu laboratory formulation was estimated to be about 6.21+/-1.03%, 5.3+/-1.21% and 4.95+/-2.34% (w/w), respectively. Piperine was found to be 7.31+/-2.36% (Piper longum), 8.41+/-2.54% (Piper nigrum), 7.89+/-2.12% (Trikatu marketed formulation) and 6.70+/-2.13% (w/w) (Trikatu laboratory formulation).
Part Used : ผลActivity : DRUG INTERACTIONSolvent/Active Compound : Trikatu laboratory formulation / DMSOType of experiment : in vitroType of animal : -Type of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : -Dose/Conc.(herb) : 100 micrograms/mLDuration : -Type of interaction : PharmacokineticsInteraction with drug : -Dose/Conc.(drug) : -Result : PositiveRemark : Results: Extract of the formulations and its ingredients had higher solubility in DMSO than ethanol. It illustrated the highest percentage of inhibition: 37.54+/-3.12% (Trikatu marketed formulation), 35.12+/-2.31% (Trikatu laboratory formulation), 33.23+/-2.56% (6-gingerol), 31.36+/-3.42% (piperine), 17.35+/+1.50% (Zingiber officinale), 20.21+/-1.86% (Piper longum), and 16.67+/-2.83% (Piper nigrum). Lowest inhibition (24.81+/-2.57% and 26.38+/-2.57%) of piperine and 6-gingerol was observed with ethanol.Note : Type of experiment: rat liver microsomes. The amount of 6-gingerol present in extract of Zingiber officinal, Trikatumarketed formulation and Trikatu laboratory formulation was estimated to be about 6.21+/-1.03%, 5.3+/-1.21% and 4.95+/-2.34% (w/w), respectively. Piperine was found to be 7.31+/-2.36% (Piper longum), 8.41+/-2.54% (Piper nigrum), 7.89+/-2.12% (Trikatu marketed formulation) and 6.70+/-2.13% (w/w) (Trikatu laboratory formulation).
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : Essential oilType of experiment : humanType of animal : -Type of study : Cross-sectionN(Total) : 354* (M/F=114/240)N(Treatment) : 5 of 29Sex : Both sexAge : The majorities (40.1%) of the respondents' were between 35-44 yrs.Route : Oral administrationDose/Conc.(herb) : Half cup/glass (6.9%), 1 cup/glass (6.9%), 1-2 spoonful (10.3%) (data analyzed from 29 of 354 patients who used herbal drugs)Duration : Once daily (58.6%), many times daily (6.9%), weekly (10.3%), occasionally (24.1%) (data analyzed from 29 of 354 patients who used herbal drugs)Type of interaction : Non-specifiedInteraction with drug : Zidovudine*/AZT/ZDV/AzidothymidineDose/Conc.(drug) : -Result : PositiveRemark :Note : *Subject total: Subjects were HIV patients. **Subject treatment: 29 of 354 patients used herbal drugs. Result: A marginal improvement though not significant (p>/=0.05) in the CD4 counts (489.8+/-195.2; 419.1+/-236.2) and viral load (5117.8+/-26092.0;31136.7+/-197954.6) of HIV patients on herbal drugs compared to those who are not on herbal drugs. There are no significant associations (p>/=0.05) between socio-demographic data and use of herbal medicine. However, there is a significant difference (p
