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ZINGIBERACEAE Zingiber officinale Roscoe

Synonym

none ...

Thai / English name

ขิง*

[2-3] of 3 article(s) found

หน้า 1 2

[2] SYNERGISTIC EFFECT OF GINGER AND NIFEDIPINE ON HUMAN PLATELET AGGREGATION: A STUDY IN HYPERTENSIVE PATIENTS AND NORMAL VOLUNTEERS.
YOUNG H-Y,LIAO J-C,CHANG Y-S,ET AL.
AM J CHIN MED 2006 Vol.34(4),545-51 $30843 [Full]

Part Used : ไม่ระบุ
Activity : ANTIPLATELET ACTIVITY

Solvent/Active Compound : -

Type of experiment : human
Type of animal : -

Type of study : non specified

N(Total) : 10
N(Treatment) : 10

Sex : Both sex
Age : 35-60 years

Route : Oral administration
Dose/Conc.(herb) : 1 g

Duration : 7 days
Type of interaction : P.Kinetics & P.Dynamics

Interaction with drug : Nifedipine
Dose/Conc.(drug) : 10 mg

Result : Positive

Remark : Subjects: hypertensive patients Results: After the treatment of the combination of nifedipine and ginger, the percentage of inhibition values with the three agonist were 64.2%, 63.8%, 61.1% respectively in hypertensive patients.

Part Used : ไม่ระบุ
Activity : DRUG INTERACTION

Solvent/Active Compound : -

Type of experiment : human
Type of animal : -

Type of study : non specified

N(Total) : 10
N(Treatment) : 10

Sex : Both sex
Age : 35-60 years

Route : Oral administration
Dose/Conc.(herb) : 1 g

Duration : 7 days
Type of interaction : P.Kinetics & P.Dynamics

Interaction with drug : Nifedipine
Dose/Conc.(drug) : 10 mg

Result : Positive

Remark : Subjects: hypertensive patients Results: After the treatment of the combination of nifedipine and ginger, the percentage of inhibition values with the three agonist were 64.2%, 63.8%, 61.1% respectively in hypertensive patients.

[3] DRUG INTERACTIONS WITH GARLIC AND GINGER SUPPLEMENTS.
ABOU-DIWAN,CHARBEL;RITCHIE,JAMES.
HERBAL SUPPLEMENTS 2011 Vol.(),333-50 $60025 [Full]

Part Used : เหง้า
Activity : DRUG INTERACTION

Solvent/Active Compound : -

Type of experiment : human
Type of animal : -

Type of study : non specified

N(Total) : -
N(Treatment) : -

Sex : -
Age : -

Route : Oral administration
Dose/Conc.(herb) : 1 g

Duration : -
Type of interaction : Pharmacodynamics

Interaction with drug : Nifedipine
Dose/Conc.(drug) : 10 mg/day

Result : Positive

Remark : It was reported that either aspirin or ginger could potentiated the antiplatelet aggregation effect of nifedipine in both patient sets. These results suggested a synergistic effect of ginger and nifedipine on antiplatelet aggregation. It has been recommended that 1 g ginger combined with 10 mg nifedipine/day could potentially combat cardiovascular and cerebrovascular complicaiton due to platelet aggregation.

Note : Data incomplete, data from review article

หน้า 1 2

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