ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

Part Used : ราก

Activity : CYCLOOXYGENASE 2 INHIBITION

Solvent/Active Compound : Curcumin (Cur)

Type of experiment : in vitro

Type of animal : -

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : -

Dose/Conc.(herb) : curcumin 0-20 micromolar

Duration : -

Type of interaction : Pharmacodynamics

Interaction with drug : Celecoxib

Dose/Conc.(drug) : 0-40 micromolar

Result : Positive

Remark :

Note : Result: A synergistic effect was observed in inhibition of cell growth when the cells were exposed to various concentrations of celecoxib combined with curcumin. The inhibitory effect of the combination on cell growth was associated with an increased induction of apoptosis. The synergistic effect was mediated through a mechanism that involves inhibition of COX-2 activity. Data incomplete

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