ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

Part Used : เหง้า

Activity : DRUG INTERACTION

Solvent/Active Compound : -

Type of experiment : in vitro

Type of animal : -

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : -

Dose/Conc.(herb) : -

Duration : -

Type of interaction : P.Kinetics & P.Dynamics

Interaction with drug : Oxacillin*/Oxazocillin/Methylphenylisoxazolyl (MPI) penicillin/Oxacilline/Oxacillinum

Dose/Conc.(drug) : -

Result : Positive

Remark : The time kill curves showed that a combined curcumin and oxacillin treatment reduced the bacterial counts below the lowest detectable limit after 24 h. This study suggested that curcumin reduced the minimal inhibitory concentration (MIC) of several antibiotics tested, notably of oxacillin, ampicillin, ciprofloxacin and norfloxacin, and that curcumin in combination with antibiotics could lead to the development of new combination of antibiotics against Methicillin-resistant Stapphylococcus aureus (MRSA) infection.

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