Part Used : หัว
Activity : EFFECTS ON PHARMACOKINETIC
Solvent/Active Compound : -
Type of experiment : human
Type of animal : -
Type of study : non specified
N(Total) : 10 (M/F=5/5)
N(Treatment) : 10
Route : Oral administration
Dose/Conc.(herb) : 2 garlic capsules (10 mg of odorless garlic extract)
Duration : 4 days
Type of interaction : Pharmacokinetics
Interaction with drug : Ritonavir
Dose/Conc.(drug) : 400 mg, single dose
Remark : In a trial of the HIV - 1 protease inhibitor ritonavir, the administration of two garlic capsules (10 mg of natural source odorless garlic extract) for 4 days in healthy volunteers did not significantly alter its single - dose pharmacokinetics.
Note : Data incomplete, data from review article