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| Thai / English name |
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : atorvastatin (10 mg/kg) + garlic (1% w/w)Duration : 12 weeksType of interaction : PharmacokineticsInteraction with drug : AtorvastatinDose/Conc.(drug) : 10 mg/kgResult : PositiveRemark : Results: The study revealed higher values [C(max), AUC, Area Under The Moment Curve (AUMC), mean resident time (MRT), and half-life] of atorvastatin in garlic-treated groups.Note : Type of experiment: Rats with induced dyslipidemia were divided into five groups. Group 1 was given atorvastatin (10 mg/kg body weight (b. wt) orally), group 2 was given atorvastain (10 mg/kg b.wt orally)+garlic (1% w/w in feed), group 3 was maintained on atorvastatin (5 mg/kg b.wt orally)+garlic (0.5% w/w in feed), group 4 was maintained on atorvastain (7.5 mg/kg b.wt orally)+garlic (0.25% w/w in feed), and group 5 was maintained on atorvastatin (2.5 mg/kg b.wt orally)+garlic (0.75% w/w in feed).
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : atorvastatin (5 mg/kg) + garlic (0.5% w/w)Duration : 12 weeksType of interaction : PharmacokineticsInteraction with drug : AtorvastatinDose/Conc.(drug) : 10 mg/kgResult : PositiveRemark : Results: The study revealed higher values [C(max), AUC, Area Under The Moment Curve (AUMC), mean resident time (MRT), and half-life] of atorvastatin in garlic-treated groups.Note : Type of experiment: Rats with induced dyslipidemia were divided into five groups. Group 1 was given atorvastatin (10 mg/kg body weight (b. wt) orally), group 2 was given atorvastain (10 mg/kg b.wt orally)+garlic (1% w/w in feed), group 3 was maintained on atorvastatin (5 mg/kg b.wt orally)+garlic (0.5% w/w in feed), group 4 was maintained on atorvastain (7.5 mg/kg b.wt orally)+garlic (0.25% w/w in feed), and group 5 was maintained on atorvastatin (2.5 mg/kg b.wt orally)+garlic (0.75% w/w in feed).
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : atorvastatin (7.5 mg/kg) + garlic (0.25% w/w)Duration : 12 weeksType of interaction : PharmacokineticsInteraction with drug : AtorvastatinDose/Conc.(drug) : 10 mg/kgResult : PositiveRemark : Results: The study revealed higher values [C(max), AUC, Area Under The Moment Curve (AUMC), mean resident time (MRT), and half-life] of atorvastatin in garlic-treated groups.Note : Type of experiment: Rats with induced dyslipidemia were divided into five groups. Group 1 was given atorvastatin (10 mg/kg body weight (b. wt) orally), group 2 was given atorvastain (10 mg/kg b.wt orally)+garlic (1% w/w in feed), group 3 was maintained on atorvastatin (5 mg/kg b.wt orally)+garlic (0.5% w/w in feed), group 4 was maintained on atorvastain (7.5 mg/kg b.wt orally)+garlic (0.25% w/w in feed), and group 5 was maintained on atorvastatin (2.5 mg/kg b.wt orally)+garlic (0.75% w/w in feed).
Part Used : ไม่ระบุActivity : DRUG INTERACTIONSolvent/Active Compound : -Type of experiment : in vivoType of animal : ratType of study : -N(Total) : -N(Treatment) : -Sex : -Age : -Route : Oral administrationDose/Conc.(herb) : atorvastatin (2.5 mg/kg) + garlic (0.75% w/w)Duration : 12 weeksType of interaction : PharmacokineticsInteraction with drug : AtorvastatinDose/Conc.(drug) : 10 mg/kgResult : PositiveRemark : Results: The study revealed higher values [C(max), AUC, Area Under The Moment Curve (AUMC), mean resident time (MRT), and half-life] of atorvastatin in garlic-treated groups.Note : Type of experiment: Rats with induced dyslipidemia were divided into five groups. Group 1 was given atorvastatin (10 mg/kg body weight (b. wt) orally), group 2 was given atorvastain (10 mg/kg b.wt orally)+garlic (1% w/w in feed), group 3 was maintained on atorvastatin (5 mg/kg b.wt orally)+garlic (0.5% w/w in feed), group 4 was maintained on atorvastain (7.5 mg/kg b.wt orally)+garlic (0.25% w/w in feed), and group 5 was maintained on atorvastatin (2.5 mg/kg b.wt orally)+garlic (0.75% w/w in feed).
