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| Thai / English name |
Part Used : หัวActivity : DRUG INTERACTIONSolvent/Active Compound : Aged garlic extractType of experiment : humanType of animal : -Type of study : Case-controlN(Total) : 10N(Treatment) : 10Sex : -Age : 45.32+/-7.96 yrs.Route : Oral administrationDose/Conc.(herb) : 600 mg/dayDuration : 7 daysType of interaction : PharmacodynamicsInteraction with drug : CelecoxibDose/Conc.(drug) : 10 mg/dayResult : NegativeRemark : Results: coadministration of garlic and cilostazol in single and multiple doses for seven days did not produce any significant change in the antiplatelet activity of the individual drugs.Note : Subject total: Type ll diabetic patients. After an overnight fast and 12 hours after the last antidiabetic medication dose, subjects were randomized in a 4-way crossover design to receive either 600 mg of garlic, 100 mg of cilostazol, 600 mg garlic + 100 mg cilostazol, or placebo, once daily for 7 days as per the randomization table. Blood samples for platelet aggregation were taken immediately before (0 hours) and 2, 4, and 6 hours after the drug treatment on first day.
Part Used : หัวActivity : DRUG INTERACTIONSolvent/Active Compound : Aged garlic extractType of experiment : humanType of animal : -Type of study : Open trialN(Total) : 10N(Treatment) : 10Sex : -Age : 45.32+/-7.96 yrs.Route : Oral administrationDose/Conc.(herb) : 600 mg/dayDuration : 7 daysType of interaction : PharmacodynamicsInteraction with drug : CelecoxibDose/Conc.(drug) : 10 mg/dayResult : NegativeRemark : Results: coadministration of garlic and cilostazol in single and multiple doses for seven days did not produce any significant change in the antiplatelet activity of the individual drugs.Note : Subject total: Type ll diabetic patients. After an overnight fast and 12 hours after the last antidiabetic medication dose, subjects were randomized in a 4-way crossover design to receive either 600 mg of garlic, 100 mg of cilostazol, 600 mg garlic + 100 mg cilostazol, or placebo, once daily for 7 days as per the randomization table. Blood samples for platelet aggregation were taken immediately before (0 hours) and 2, 4, and 6 hours after the drug treatment on first day.
Part Used : หัวActivity : DRUG INTERACTIONSolvent/Active Compound : Aged garlic extractType of experiment : humanType of animal : -Type of study : Cross overN(Total) : 10N(Treatment) : 10Sex : -Age : 45.32+/-7.96 yrs.Route : Oral administrationDose/Conc.(herb) : 600 mg/dayDuration : 7 daysType of interaction : PharmacodynamicsInteraction with drug : CelecoxibDose/Conc.(drug) : 10 mg/dayResult : NegativeRemark : Results: coadministration of garlic and cilostazol in single and multiple doses for seven days did not produce any significant change in the antiplatelet activity of the individual drugs.Note : Subject total: Type ll diabetic patients. After an overnight fast and 12 hours after the last antidiabetic medication dose, subjects were randomized in a 4-way crossover design to receive either 600 mg of garlic, 100 mg of cilostazol, 600 mg garlic + 100 mg cilostazol, or placebo, once daily for 7 days as per the randomization table. Blood samples for platelet aggregation were taken immediately before (0 hours) and 2, 4, and 6 hours after the drug treatment on first day.
