ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

Part Used : -

Activity : CYP3A1 INDUCTION

Solvent/Active Compound : diallyl disulfide

Type of experiment : in vitro

Type of animal : -

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : -

Dose/Conc.(herb) : -

Duration : -

Type of interaction : Pharmacokinetics

Interaction with drug : Cyclophosphamide*/CPM/CTX/CYT

Dose/Conc.(drug) : -

Result : Positive

Remark : Type of experiment = maternal liver and placenta

Note : Diallyl disulfide (DADS) treatment significantly attenuated cyclophosphamide-induced developmental toxicity and oxidative damage in the maternal liver. DADS also significantly increased expression of CYP3A1 in the maternal liver placenta.

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