Part Used : เหง้า
Activity : DRUG INTERACTION
Solvent/Active Compound :
Type of experiment : in vitro
Type of animal : -
N(Total) : -
N(Treatment) : -
Route : -
Dose/Conc.(herb) : 100 microgram/ml
Duration : 30 minutes
Type of interaction : Pharmacokinetics
Interaction with drug : Docetaxel*/Taxotere
Dose/Conc.(drug) : -
Remark : - Details of the standardized Garlic extracts: Garlic extract 100:1 (m/m), Allicin scordinin alliin.
Note : The effects of complementary and alternative medicine (CAM) on CYP3A4-mediated metabolism of midazolam and docetaxel were determined in human liver microsomes (HLM), using liquid-chromatography coupled to tandem mass spectrometry (LC-MS/MS).