ฐานข้อมูลอันตรกิริยาระหว่างสมุนไพรกับยาแผนปัจจุบัน

Part Used : ใบ

Activity : CYP1A2 INDUCTION

Solvent/Active Compound : Methanolic extract

Type of experiment : in vitro

Type of animal : -

Type of study : -

N(Total) : -

N(Treatment) : -

Sex : -

Age : -

Route : -

Dose/Conc.(herb) : -

Duration : -

Type of interaction : Pharmacokinetics

Interaction with drug : Rifampicin*/Rifampin

Dose/Conc.(drug) : -

Result : Positive

Remark : The mRNA expression of P-gp and CYP1A2 was also increased by the extract, alkaloid rich fraction and 4 of the constituents, while the expression of CYP3A4 was increased by the alkaloid rich fraction and 3 of the constituents.

Note : Data incomplete

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